Full text [open access]
Journal Article
SARS-CoV-2 breath tests implementation for the rapid COVID-19 surveillance: a game changer? A review of existing data.
Vallejo Degaudenzi, Alejandro G.
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Hernández, Daniela M.
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Hidalgo Rosario, Daniela I.
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Contreras Matos, Elisa
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Ceballos Villacampa, María Laura
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Polanco Valdez, Mariel
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Reynoso Ortega, Máximo Elías
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Hernández Quezada, Nicole
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Marranzini, Camila
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Paulino-Ramírez, Robert
| Fecha de publicación | Revista | DOI |
2022 |
Resumen
The Coronavirus Disease 2019 (COVID-19) pandemic has been spread across the globe for almost a year, causing economic, social, and psychological impacts with yet unknown dimensions. In emerging and reemerging pathogen surveillance and detection, polymerase chain reaction (PCR) is a classic laboratory technique that has been widely used for the amplification and identification of nucleic acids. Analysis of volatile organic compounds (VOCs) in breath has been long reviewed as a potential diagnostics tool for many diseases. The overall specificity for SARS-CoV-2 of these methods was a calculated 69%,30 which is a low value for reliable detection. Breath tests are not a sufficiently evidence-based approach for rapid screening and to "secure" or creating "sanctuary" regions for touristic purposes. Therefore, policy-makers must cautiously point out the importance of further evaluation and structured studies confronting gold-standards with new devices.