Please use this identifier to cite or link to this item: http://cris.unibe.edu.do/handle/123456789/141
Title: Phenylketonuria: central nervous system and microbiome interaction
Autores: Herrera Morban, Demian Arturo
Researchers (UNIBE): Herrera Morban, Demian Arturo 
Affiliations: Facultad de Ciencias de la Salud 
Research area: Ciencias de la Salud
Keywords: Phenylalanine; Phenylketonuria; Microbiome; Glial cells; Neurogenesis
Issue Date: 2017
Publisher: Hygeia Press di Corridori Marinella
Source: Journal of Pediatric and Neonatal Individualized Medicine, 6(2), e060207
Journal: Journal of Pediatric and Neonatal Individualized Medicine 
Volume: 6
Issue: 2
Start page: e060207
Abstract: 
Phenylketonuria (PKU) is an autosomal recessive inborn error of metabolism characterized by increased phenylalanine (Phe) levels causing an inadequate neurodevelopment; the treatment of PKU is a Phe-restricting diet, and as such it can modulate the intestinal microbiome of the individual, generating central nervous system secondary disturbances that, added to the baseline disturbance, can influence the outcome of the disease.
URI: http://cris.unibe.edu.do/handle/123456789/141
DOI: 10.7363/060207
Appears in Collections:Publicaciones de la Facultad de Ciencias de la Salud

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