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Title: Prevalence of HTLV infection in the Dominican Republic: association with neurological disease
Autores: Koenig, R. Ellen
Tolentino, M.
Taveras, L.
Ferro, F.
Zornoso, C.
Ferreiras, J.
Matos, G.
Oquist, Cheri
Capellán, M.
Amorós, Carlos
Gatón, Federico
Lavandera, María
De Castro, L.
Connely, M.
Levy, J. A.
Researchers (UNIBE): Koenig, R. Ellen 
Oquist, Cheri 
Amorós, Carlos 
Gatón, Federico 
Lavandera, María 
Affiliations: Facultad de Ciencias de la Salud 
Facultad de Ciencias de la Salud 
Facultad de Ciencias de la Salud 
Facultad de Ciencias de la Salud 
Facultad de Ciencias de la Salud 
Research area: Ciencias de la Salud
Issue Date: 1992
Publisher: Mary Ann Liebert, Inc.
Source: AIDS research and human retroviruses, 8(2), 221-226
Journal: AIDS research and human retroviruses 
Volume: 8
Issue: 2
Start page: 221
End page: 226
The presence of the human T-cell leukemia virus (HTLV) in Dominican blood donors and patients with tropical spastic paraparesis (TSP) was first detected in 1987. To define further the seroprevalence in the country, nearly 4,000 samples from high- and low-risk populations, as well as patients with neurological disease and with leukemia or lymphoma were tested for HTLV antibodies. A 1-2% seropositivity rate was found among the low-risk population, a 2-5% in the high-risk, and at least 87% in those with TSP. A few patients with malignancy also had antibodies to HTLV. An increase in seropositivity with age and a predominance of female seropositive individuals were found. Infectious virus was isolated from TSP patients, prostitutes, and family members of index patients. These data indicate the substantial level of HTLV infection in another Caribbean country and its relation to neurologic disease.
DOI: 10.1089/aid.1992.8.221
Appears in Collections:Publicaciones del Área de Salud - Medicina
Publicaciones indexadas en Scopus / Web of Science

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