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dc.contributor.authorSantos Germán, Iris Jasmin-
dc.date.accessioned2022-02-20T20:14:15Z-
dc.date.available2022-02-20T20:14:15Z-
dc.date.issued2020-
dc.identifier.citationMaterials, 13(3), 695-
dc.identifier.urihttp://cris.unibe.edu.do/handle/123456789/261-
dc.description.abstractTo assess the effects of chronic alcoholism on the repair of bone defects associated with xenograft. Forty male rats were distributed in: control group (CG, n = 20) and experimental group (EG, n = 20), which received 25% ethanol ad libitum after a period of adaptation. After 90 days of liquid diet, the rats were submitted to 5.0-mm bilateral craniotomy on the parietal bones, subdividing into groups: CCG (control group that received only water with liquid diet and the defect was filled with blood clot), BCG (control group that received only water with liquid diet and the defect was filled with biomaterial), CEG (alcoholic group that received only ethanol solution 25% v/v with liquid diet and the defect was filled with blood clot), and BEG (alcoholic group that received only ethanol solution 25% v/v with liquid diet and the defect was filled with biomaterial). In the analysis of body mass, the drunk animals presented the lowest averages in relation to non-drunk animals during the experimental period. Histomorphologically all groups presented bone formation restricted to the defect margins at 60 days, with bone islets adjacent to the BCG biomaterial particles. CEG showed significant difference compared to BEG only at 40 days (17.42 ± 2.78 vs. 9.59 ± 4.59, respectively). In the birefringence analysis, in early periods all groups showed red-orange birefringence turning greenish-yellow at the end of the experiment. The results provided that, regardless of clinical condition, i.e., alcoholic or non-alcoholic, in the final period of the experiment, the process of bone defect recomposition was similar with the use of xenograft or only clot.en
dc.language.isoEnglish-
dc.publisherMDPI Multidisciplinary Digital Publishing Institute-
dc.relation.ispartofMaterials-
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/-
dc.subjectCiencias de la Salud-
dc.titleEvaluation of the use of an inorganic bone matrix in the repair of bone defects in rats submitted to experimental alcoholismen
dc.typeJournal Article-
dc.rights.licenseThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.-
dc.identifier.doi10.3390/ma13030695-
dc.identifier.pmid32033088-
dc.rights.holder© 2020 by the authors. Licensee MDPI, Basel, Switzerland.-
dc.contributor.affiliationFacultad de Ciencias de la Salud-
dc.identifier.pmcidPMC7040897-
dc.relation.issn1996-1944-
dc.description.volume13-
dc.description.issue3-
dc.description.startpage695-
dc.subject.keywordsAlcoholen
dc.subject.keywordsAlcoholismen
dc.subject.keywordsBiomaterialsen
dc.subject.keywordsBone repairen
dc.contributor.authorsSantos Germán, Iris Jasmin-
dc.contributor.authorsTorres Pomini, K.-
dc.contributor.authorsCestari Bighetti, A. C.-
dc.contributor.authorsAndreo, J. C.-
dc.contributor.authorsBertoni Reis, C. H.-
dc.contributor.authorsShinohara, A. L.-
dc.contributor.authorsRosa Júnior, G. M.-
dc.contributor.authorsDe Bortoli Teixeira, D.-
dc.contributor.authorsDe Oliveira Rosso, M. P.-
dc.contributor.authorsVieira Buchaim, D.-
dc.contributor.authorsLeone Buchaim, R.-
dc.typeofaccessOpen Access-
dc.contributor.affiliationinstitutionUniversidad Iberoamericana (UNIBE)-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of Marilia-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversidade Nove de Julho-
dc.contributor.affiliationinstitutionUniversity of Marilia-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of Marilia-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationcountryDominican Republic-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.languageiso639-1English-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextCon texto completo -
crisitem.author.deptFacultad de Ciencias de la Salud-
crisitem.author.parentorgUniversidad Iberoamericana (UNIBE)-
Aparece en las colecciones: Publicaciones del Área de Salud - Medicina
Publicaciones indexadas en Scopus / Web of Science
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