Please use this identifier to cite or link to this item: http://cris.unibe.edu.do/handle/123456789/262
DC FieldValueLanguage
dc.contributor.authorSantos Germán, Iris Jasmin-
dc.date.accessioned2022-02-20T20:40:43Z-
dc.date.available2022-02-20T20:40:43Z-
dc.date.issued2019-
dc.identifier.citationInternational Journal of Molecular Sciences, 20(7), 1761-
dc.identifier.urihttp://cris.unibe.edu.do/handle/123456789/262-
dc.description.abstractFibrin sealants derived from human blood can be used in tissue engineering to assist in the repair of bone defects. The objective of this study was to evaluate the support system formed by a xenograft fibrin sealant associated with photobiomodulation therapy of critical defects in rat calvaria. Thirty-six rats were divided into four groups: BC (n = 8), defect filled with blood clot; FSB (n = 10), filled with fibrin sealant and xenograft; BCPBMT (n = 8), blood clot and photobiomodulation; FSBPBMT (n = 10), fibrin sealant, xenograft, and photobiomodulation. The animals were killed after 14 and 42 days. In the histological and microtomographic analysis, new bone formation was observed in all groups, limited to the defect margins, and without complete wound closure. In the FSB group, bone formation increased between periods (4.3 ± 0.46 to 6.01 ± 0.32), yet with lower volume density when compared to the FSBPBMT (5.6 ± 0.45 to 10.64 ± 0.97) group. It was concluded that the support system formed by the xenograft fibrin sealant associated with the photobiomodulation therapy protocol had a positive effect on the bone repair process.en
dc.language.isoEnglish-
dc.publisherMDPI Multidisciplinary Digital Publishing Institute-
dc.relation.ispartofInternational Journal of Molecular Sciences-
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/-
dc.subjectCiencias de la Salud-
dc.titleFibrin sealant derived from human plasma as a scaffold for bone grafts associated with photobiomodulation therapyen
dc.typeJournal Article-
dc.rights.licenseThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.-
dc.identifier.doi10.3390/ijms20071761-
dc.identifier.pmid30974743-
dc.rights.holder© 2019 by the authors. Licensee MDPI, Basel, Switzerland.-
dc.contributor.affiliationFacultad de Ciencias de la Salud-
dc.identifier.pmcidPMC6479442-
dc.relation.issn1422-0067-
dc.description.volume20-
dc.description.issue7-
dc.description.startpage1761-
dc.subject.keywordsBone generationen
dc.subject.keywordsBone repairen
dc.subject.keywordsBiomaterialen
dc.subject.keywordsFibrin sealanten
dc.subject.keywordsPhotobiomodulation therapyen
dc.subject.keywordsLow-level laser therapyen
dc.contributor.authorsTorres Pominia, K.-
dc.contributor.authorsVieira Buchaim, D.-
dc.contributor.authorsAndreo, J. C.-
dc.contributor.authorsDe Oliveira Rosso, M. P.-
dc.contributor.authorsBotteon Della Coletta, B.-
dc.contributor.authorsSantos Germán, Iris Jasmin-
dc.contributor.authorsCestari Bighetti, A. C.-
dc.contributor.authorsShinohara, A. L.-
dc.contributor.authorsRosa Júnior, G. M.-
dc.contributor.authorsTadashi Cosin Shindo, J. V.-
dc.contributor.authorsPriori Alcalde, M.-
dc.contributor.authorsHungaro Duarte, M. A.-
dc.contributor.authorsDe Bortoli Teixeira, D.-
dc.contributor.authorsLeone Buchaim, R.-
dc.typeofaccessOpen Access-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversidad Iberoamericana (UNIBE)-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of the Sacred Heart-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of the Sacred Heart-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationinstitutionUniversity of Marilia-
dc.contributor.affiliationinstitutionUniversity of São Paulo-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryDominican Republic-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
dc.contributor.affiliationcountryBrazil-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1English-
item.openairetypeJournal Article-
item.grantfulltextopen-
item.fulltextCon texto completo -
crisitem.author.deptFacultad de Ciencias de la Salud-
crisitem.author.parentorgUniversidad Iberoamericana (UNIBE)-
Appears in Collections:Publicaciones de la Facultad de Ciencias de la Salud
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