Frequency of non-AIDS defining events in patients infected with HIV in an outpatient clinic in Santo Domingo, Dominican Republic

Abstract

Chronic Liver Disease accounted for 26.3% of the presented non-AIDS defining events. Hypercholesterolemia accounted for 20%, Dyslipidemia 17.5%, Chronic Kidney Disease 6.3% and Anal Dysplasia 3.8% of the cases. Male patients were the most commonly affected gender representing 55.4% cases, followed by female patients with 35.4% cases. The most affected vulnerable population were MSM with 18.5% cases, sexual workers accounted for 15.4% of cases. 91% were adherent to HAART. 82% cases had a cd4+/cd8+ proportion <1. Although most of the patients that were studied remained adherent to the antiretroviral therapy non-AIDS defining events were still observed and the proportion of CD4 + / CD8 + lymphocytes remained <1 in the majority of the cases, reflecting the immunosenescence that can be observed in the vast majority of HIV-infected patients, possibly increasing their risk of suffering a defining or non-defining event of AIDS. The vulnerable populations of MSM and sexual workers affected with higher frequency.