Please use this identifier to cite or link to this item: http://cris.unibe.edu.do/handle/123456789/294
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dc.contributor.authorShirin, Shah-
dc.date.accessioned2022-02-26T01:25:50Z-
dc.date.available2022-02-26T01:25:50Z-
dc.date.issued2015-
dc.identifier.citationNorth American Journal of Medical Sciences, 7(11), 494-502-
dc.identifier.urihttp://cris.unibe.edu.do/handle/123456789/294-
dc.description.abstractUpper airway hematoma (UAH) is a rare but life-threatening complication of oral anticoagulants requiring early recognition. However, no consensus exists regarding the best approach to treatment. We therefore, sought to systematically review the published literature on UAH to elaborate its demographic and clinical characteristics, treatment, complications, and outcomes. A systematic electronic search of PubMed and EMBASE for case reports, case series, and related articles of UAH related to warfarin published from inception (November 1950) to March 2015 was carried out. Categorical variables were expressed as percentage and continuous variables as mean ± standard deviation (SD). Statistical analysis was done using Statistical Package for the Social Sciences (SPSS) version 20.0. All cases were reported to have UAH as a complication of anticoagulation therapy with warfarin. Demographic and clinical characteristics, treatment, complications and outcomes of UAH were studied. Thirty-eight cases of UAH were identified from 34 reports in the literature. No gender preponderance (male = 52.78%) was seen and the average age of presentation was 60.11 ± 12.50 years. Dysphagia, sore throat, and neck swelling were the most common symptoms and the mean international normalized ratio (INR)at presentation was 8.07 ± 4.04. Most cases had sublingual hematoma (66.57%) followed by retropharyngeal hematoma (27.03%). Of the cases, 48.65% were managed conservatively while the rest underwent either cricothyrotomy or intubation with the time to resolution being 7.69 ± 5.44 days. UAH is a rare butpotentially serious complication of warfarin therapy. It is more common in the elderly population with supratherapeutic INR; inciting events were present in many cases. Overall, it has a good prognosis with significant morbidity present only if concomitant respiratory compromise is present. Reversal of anticoagulation with low threshold for artificial airway placement in the event of airway compromise leads to a favorable outcome in most cases.en
dc.language.isoEnglish-
dc.publisherWolters Kluwer Medknow Publications-
dc.relation.ispartofNorth American Journal of Medical Sciences-
dc.subjectCiencias de la Salud-
dc.titleUpper airway hematoma secondary to warfarin therapy: a systematic review of reported casesen
dc.typeReview Article-
dc.identifier.doi10.4103/1947-2714.170606-
dc.identifier.pmid26713297-
dc.rights.holder© 2015 North American Journal of Medical Sciences | Published by Wolters Kluwer - Medknow-
dc.contributor.affiliationFacultad de Ciencias de la Salud-
dc.identifier.pmcidPMC4683804-
dc.relation.issn1947-2714-
dc.description.volume7-
dc.description.issue11-
dc.description.startpage494-
dc.description.endpage502-
dc.subject.keywordsAirway obstructionen
dc.subject.keywordsHematomaen
dc.subject.keywordsMouth flooren
dc.subject.keywordsWarfarinen
dc.contributor.authorsKarmacharya, P.-
dc.contributor.authorsPathak, R.-
dc.contributor.authorsGhimire, S.-
dc.contributor.authorsShrestha, P.-
dc.contributor.authorsGhimire, S.-
dc.contributor.authorsPoudel, D. R.-
dc.contributor.authorsKhanal, R.-
dc.contributor.authorsShah, Shirin-
dc.contributor.authorsAryal, M. R.-
dc.contributor.authorsAlweis , R. L.-
dc.typeofaccessOpen Access-
dc.contributor.affiliationinstitutionReading Health System-
dc.contributor.affiliationinstitutionReading Health System-
dc.contributor.affiliationinstitutionCollege of Medical Sciences-
dc.contributor.affiliationinstitutionNanjing Medical University-
dc.contributor.affiliationinstitutionReading Health System-
dc.contributor.affiliationinstitutionReading Health System-
dc.contributor.affiliationinstitutionReading Health System-
dc.contributor.affiliationinstitutionUniversidad Iberoamericana (UNIBE)-
dc.contributor.affiliationinstitutionReading Health System-
dc.contributor.affiliationinstitutionReading Health System-
dc.contributor.affiliationcountryUSA-
dc.contributor.affiliationcountryUSA-
dc.contributor.affiliationcountryIndia-
dc.contributor.affiliationcountryChina-
dc.contributor.affiliationcountryUSA-
dc.contributor.affiliationcountryUSA-
dc.contributor.affiliationcountryUSA-
dc.contributor.affiliationcountryDominican Republic-
dc.contributor.affiliationcountryUSA-
dc.contributor.affiliationcountryUSA-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1English-
item.openairetypeReview Article-
item.grantfulltextopen-
item.fulltextCon texto completo -
crisitem.author.deptFacultad de Ciencias de la Salud-
crisitem.author.parentorgUniversidad Iberoamericana (UNIBE)-
Appears in Collections:Publicaciones de la Facultad de Ciencias de la Salud
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