Please use this identifier to cite or link to this item:
http://cris.unibe.edu.do/handle/123456789/301
DC Field | Value | Language |
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dc.contributor.author | Olivero García, Jiohanna M. | - |
dc.date.accessioned | 2022-02-26T20:35:57Z | - |
dc.date.available | 2022-02-26T20:35:57Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Annals of translational medicine, 7(16), 393 | - |
dc.identifier.uri | http://cris.unibe.edu.do/handle/123456789/301 | - |
dc.description.abstract | Obesity is a chronic, relapsing, multifactorial disease, which has become a serious threat to public health globally, as the worldwide prevalence of obesity increases exponentially over time. It has been well established that obesity is associated with multiple adverse cardiometabolic effects. Although lifestyle changes are the first line of therapy for obesity, these are often insufficient in attaining weight loss goals. Orlistat, phentermine/topiramate, lorcaserin, naltrexone/bupropion, and liraglutide are agents that have been approved for the treatment of obesity but their effects on cardiometabolic risk factors and outcomes have not been clearly elucidated. Given the detrimental repercussions of obesity on cardiometabolic health, there is a pressing clinical need to fully understand the effects of these agents beyond weight loss alone. Certain previous weight loss drugs have been withdrawn due to safety concerns and this underlines the need for more careful assessment of the effects of the various pharmacologic agents currently used for the treatment of obesity. This review aims to provide an overview of the mechanisms, efficacy, safety and cardiometabolic effects of the currently available pharmacologic agents for weight loss. | en |
dc.language.iso | English | - |
dc.publisher | AME Publishing Company | - |
dc.relation.ispartof | Annals of Translational Medicine | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject | Ciencias de la Salud | - |
dc.title | Pharmacologic therapy of obesity: mechanisms of action and cardiometabolic effects | en |
dc.type | Review Article | - |
dc.rights.license | CC BY-NC-ND | - |
dc.identifier.doi | 10.21037/atm.2019.07.27 | - |
dc.identifier.pmid | 31555707 | - |
dc.rights.holder | © Annals of Translational Medicine. All rights reserved. | - |
dc.contributor.affiliation | Facultad de Ciencias de la Salud | - |
dc.identifier.pmcid | PMC6736799 | - |
dc.relation.issn | 2305-5839 | - |
dc.description.volume | 7 | - |
dc.description.issue | 16 | - |
dc.description.startpage | 393 | - |
dc.subject.keywords | Obesity | en |
dc.subject.keywords | Overweight | en |
dc.subject.keywords | Orlistat | en |
dc.subject.keywords | Phentermine/Topiramate | en |
dc.subject.keywords | Lorcaserin | en |
dc.subject.keywords | Naltrexone/Bupropion | en |
dc.subject.keywords | Liraglutide | en |
dc.subject.keywords | Cardiometabolic effects | en |
dc.contributor.authors | Montan, P. D. | - |
dc.contributor.authors | Sourlas, A. | - |
dc.contributor.authors | Olivero García, Jiohanna M. | - |
dc.contributor.authors | Silverio, D. | - |
dc.contributor.authors | Guzmán, E. | - |
dc.contributor.authors | Kosmas, K. E. | - |
dc.typeofaccess | Open Access | - |
dc.contributor.affiliationinstitution | Cardiology Unlimited | - |
dc.contributor.affiliationinstitution | University of Crete | - |
dc.contributor.affiliationinstitution | Universidad Iberoamericana (UNIBE) | - |
dc.contributor.affiliationinstitution | Cardiology Unlimited | - |
dc.contributor.affiliationinstitution | Montefiore Medical Center | - |
dc.contributor.affiliationinstitution | Montefiore Medical Center | - |
dc.contributor.affiliationcountry | USA | - |
dc.contributor.affiliationcountry | Greece | - |
dc.contributor.affiliationcountry | Dominican Republic | - |
dc.contributor.affiliationcountry | USA | - |
dc.contributor.affiliationcountry | USA | - |
dc.contributor.affiliationcountry | USA | - |
item.fulltext | Con texto completo | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | open | - |
item.languageiso639-1 | English | - |
item.openairetype | Review Article | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Facultad de Ciencias de la Salud | - |
crisitem.author.parentorg | Universidad Iberoamericana (UNIBE) | - |
Appears in Collections: | Publicaciones del Área de Salud - Medicina Publicaciones indexadas en Scopus / Web of Science |
Files in This Item:
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27477-PB1-5230-R2.pdf | Full text [open access] | 192.22 kB | Adobe PDF | View/Open |
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