Por favor, use este identificador para citar o enlazar este ítem: http://cris.unibe.edu.do/handle/123456789/438
Título : Travel surveillance uncovers dengue virus dynamics and introductions in the Caribbean
Autores: Taylor-Salmon, E.
Hill, V.
Paul, L. M.
Koch, R. T.
Breban, M. I.
Chaguza, C.
Sodeinde, A.
Warren, J. L.
Bunch, S.
Cano, N.
Cone, M.
Eysoldt, S.
García, A.
Gilles, N.
Hagy, A.
Heberlein, L.
Jaber, R.
Kassens, E.
Colarusso, P.
Davis, A.
Baudin, S.
Rico, E.
Mejía-Echeverri, Á.
Scott, B.
Stanek, D.
Zimler, R.
Muñoz-Jordán, J. L.
Santiago, G. A.
Adams, L. E.
Paz-Bailey, G.
Spillane, M.
Katebi, V.
Paulino-Ramírez, Robert
Mueses Jiménez, Sayira P.
Peguero J., Armando G.
Sánchez Morfe, Nelissa
Norman, F. F.
Galán, J. C.
Huits, R.
Hamer, D. H.
Vogels, C. B. F.
Morrison, A.
Michael, S. F.
Grubaugh, N. D.
Investigadores (UNIBE): Paulino-Ramírez, Robert 
Mueses Jiménez, Sayira P. 
Peguero J., Armando G. 
Sánchez Morfe, Nelissa 
Afiliaciones : Instituto de Medicina Tropical y Salud Global (IMTSAG) 
Instituto de Medicina Tropical y Salud Global (IMTSAG) 
Instituto de Medicina Tropical y Salud Global (IMTSAG) 
Instituto de Medicina Tropical y Salud Global (IMTSAG) 
Área de investigación : Ciencias de la Salud
Fecha de publicación : 2024
Editorial : Nature Publishing Group
Publicado en: Nature Communications, 15(1), 3508; 2024
Revista: Nature Communications 
Volumen : 15
Número : 3508
Página de inicio : 1
Página final : 14
Resumen : 
Dengue is the most prevalent mosquito-borne viral disease in humans, and cases are continuing to rise globally. In particular, islands in the Caribbean have experienced more frequent outbreaks, and all four dengue virus (DENV) serotypes have been reported in the region, leading to hyperendemicity and increased rates of severe disease. However, there is significant variability regarding virus surveillance and reporting between islands, making it difficult to obtain an accurate understanding of the epidemiological patterns in the Caribbean. To investigate this, we used travel surveillance and genomic epidemiology to reconstruct outbreak dynamics, DENV serotype turnover, and patterns of spread within the region from 2009-2022. We uncovered two recent DENV-3 introductions from Asia, one of which resulted in a large outbreak in Cuba, which was previously under-reported. We also show that while outbreaks can be synchronized between islands, they are often caused by different serotypes. Our study highlights the importance of surveillance of infected travelers to provide a snapshot of local introductions and transmission in areas with limited local surveillance and suggests that the recent DENV-3 introductions may pose a major public health threat in the region.
URI : http://cris.unibe.edu.do/handle/123456789/438
DOI : https://doi.org/10.1038/s41467-024-47774-8
Aparece en las colecciones: Publicaciones del IMTSAG-UNIBE

Ficheros en este ítem:
Fichero Descripción Tamaño Formato
s41467-024-47774-8.pdfFull text [open access]3.41 MBAdobe PDFVisualizar/Abrir
Mostrar el registro Dublin Core completo del ítem Recomiende este ítem

Google ScholarTM

Citas

Altmetric

Menciones

Dimensions

Citas


Este ítem está sujeto a una Licencia Creative Commons Creative Commons